Friday, March 20, 2020

solum law Essay

solum law Essay solum law Essay Chicago-Kent Law Review Volume 66 Issue 1 Symposium on Classical Philosophy and the American Constitutional Order Article 8 January 1990 Pluralism and Modernity Lawrence B. Solum Follow this and additional works at: http://scholarship.kentlaw.iit.edu/cklawreview Part of the Law Commons Recommended Citation Lawrence B. Solum, Pluralism and Modernity, 66 Chi.-Kent. L. Rev. 93 (1990). Available at: http://scholarship.kentlaw.iit.edu/cklawreview/vol66/iss1/8 This Article is brought to you for free and open access by Scholarly Commons @ IIT Chicago-Kent College of Law. It has been accepted for inclusion in Chicago-Kent Law Review by an authorized administrator of Scholarly Commons @ IIT Chicago-Kent College of Law. For more information, please contact jwhipple@kentlaw.iit.edu. PLURALISM AND MODERNITY LAWRENCE I. B. SOLUM* INTRODUCTION This essay considers the claim that liberalism offers an impoverished and narrow vision of human association. One of the classic statements of this claim is found in the early Marx. He wrote that the freedom provided by liberalism "is that of a man treated as an isolated monad and withdrawn into himself."' This conception of freedom, he continued, "is not based on the union of man with man, but on the separation of man from man. ' ' 2 Marx's critique is echoed in contemporary political philosophy. Alasdair MacIntyre writes that "Modem politics is civil war carried on by other means."'3 Michael Sandel suggests that the alternative to the liberal regime is strong community, a form of social arrangement that is "constitutive of the shared self-understandings of the participants." '4 These critics of liberalism share a picture of the liberal regime as a social order that favors a particular conception of the human good: an atomistic, individualistic conception that destroys the social basis for community and solidarity.5 Ronald Beiner, in his paper, The LiberalRegime,6 has developed the 7 critique of liberal political theory from a neo-Aristotelian perspective. He offers a powerful elaboration of the claim that liberalism produces an impoverished ethos or way of life and a strong defense of an Aristotelian alternative. I agree with much in this critique. Certainly, Aristotle's moral and political theory offers insights into contemporary debates in constitutional theory and jurisprudence," but there are two aspects of * Professor of Law and William M. Rains Fellow, Loyola Law School, Loyola Marymount University, Los Angeles, California. I owe thanks to Ron Beiner, Shelley Marks, and Sam Pillsbury for their remarks on earlier versions of this essay. 1. K. MARx, On the Jewish Question, in SELECTED WRITINGS 53 (D. McLellan ed. 1977). 2. Id. 3. A. MAcINTYRE, AFIER VIRTUE (2d ed. 1984). 4. M. SANDEL, LIBERALISM AND THE LIMITS OF JUSTICE 173 (1982). 5. See Solum, Faith and Justice, 39 DEPAUL L. REV. 1083, 1087 (1990). 6. Beiner, The Liberal Regime, 66 CHi. KENT L. REV. 73 (1990). 7. See generally ARISTOTLE, NiCOMACHEAN ETHIcs (W. Ross trans., J. Urrnson, revisions) and POLITICS (B. Jowett & J. Barnes trans.) in 2 THE COMPLETE WORKS OF ARISTOTLE (J. Barnes ed. 1984). [Hereinafter all citations to these works will refer to the pagination of the Bekker edition or to book and chapter numbers.] 8. See Solum, Virtues and Voices, 66 CHI.-KENT L. REv. 111 (1990); Solum, The Virtues and Vices of a Judge: An Aristotelian Guide to JudicialSelection, 61 S. CAL. L. REV. 1735 (1988); Bros- CHICAGO-KENT LAW REVIEW (Vol. 66:93 Beiner's paper with which I will take issue. First, I disagree with the claim that Aristotle's moral and political theory is consistent with the fact of pluralism. Second, I take issue with the charge that liberalism is defective because it entails an impoverished ethos. Before exploring these points of contention, let me introduce the concepts that are fundamental to the debate. Beiner develops his critique of

Wednesday, March 4, 2020

Genes - Definition, Function, and Mutations

Genes - Definition, Function, and Mutations Genes are segments of DNA located on chromosomes that contain the instructions for protein production. Scientists estimate that humans have as many as 25,000 genes. Genes exist in more than one form. These alternative forms are called alleles and there are typically two alleles for a given trait. Alleles determine distinct traits that can be passed on from parents to offspring. The process by which genes are transmitted was discovered by Gregor Mendel and formulated in what is known as Mendels law of segregation. Gene Transcription Genes contain the genetic codes, or  sequences of nucleotide bases in nucleic acids, for the production of specific proteins. The information contained within DNA is not directly converted to proteins, but must first be transcribed in a process called DNA transcription. This process takes place within the nucleus of our cells. Actual protein production takes place in the cytoplasm of our cells through a process called translation. Transcription factors are special proteins that determined whether or not a gene gets turned on or off. These proteins bind to DNA and either aid in the transcription process or inhibit the process. Transcription factors are important for cell differentiation as they determine which genes in a cell are expressed. The genes expressed in a red blood cell, for example, differ from those expressed in a sex cell. An Individual's Genotype In diploid organisms, alleles come in pairs. One allele is inherited from the father and the other from the mother. Alleles determine an individuals genotype or gene composition. The allele combination of the genotype determines the traits that are expressed or the phenotype. A genotype producing the phenotype of a straight hairline, for example, differs from the genotype resulting in a V-shaped hairline. Inherited Through Both Asexual and Sexual Reproduction. Genes are inherited through both asexual reproduction and sexual reproduction. In asexual reproduction, resulting organisms are genetically identical to a single parent. Examples of this type of reproduction include budding, regeneration, and parthenogenesis. Gametes Fuse to Form a Distinct Individual Sexual reproduction involves the contribution of genes from both male and female gametes that fuse to form a distinct individual. The traits exhibited in these offspring are transmitted independently of one another and may result from several types of inheritance. In complete dominance inheritance, one allele for a particular gene is dominant and completely masks the other allele for the gene.In incomplete dominance, neither allele is completely dominant over the other resulting in a phenotype that is a mixture of both parent phenotypes.In co-dominance, both alleles for a trait are fully expressed. Some Traits Determined by More Than One Gene Not all traits are determined by a single gene. Some traits are determined by more than one gene and are therefore known as polygenic traits. Some genes are located on sex chromosomes and are called sex-linked genes. There are a number of disorders that are caused by abnormal sex-linked genes including hemophilia and color blindness. Variation Helps Adapting to Changing Situations Genetic variation is a change in the genes that occur in organisms in a population. This variation typically occurs through DNA mutation, gene flow (movement of genes from one population to another) and sexual reproduction. In unstable environments, populations with genetic variation are typically able to adapt to changing situations better than those that do not contain genetic variation. Mutations Are From Errors and the Environment A gene mutation is an alteration in the sequence of nucleotides in DNA. This change can affect a single nucleotide pair or larger segments of a chromosome. Changing gene segment sequences most often results in non-functioning proteins. Some mutations can result in disease, while others may have no negative impact on or may even benefit an individual. Still, other mutations may result in unique traits such as dimples, freckles, and multicolored eyes. Gene mutations are most commonly the result of environmental factors (chemicals, radiation, ultraviolet light) or errors that occur during cell division (mitosis and meiosis).